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Stephen B. Gruber, M.D., Ph.D., M.P.H.

Medical Oncologist

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Conditions Treated Laryngeal Cancer Lung Cancer Ovarian Cancer Pericardial Mesothelioma Peritoneal Mesothelioma Pleural Mesothelioma Testicular Mesothelioma

  • Bio & Insurance Information

    Dr. Stephen Gruber is a renowned medical oncologist and also the Director of the USC Norris Comprehensive Cancer Center. He is a board certified medical oncologist, epidemiologist, and cancer geneticist that focuses particularly on genetic and environmental improvements to cancer. The main goal of his research is to discover new ways to prevent cancer and to increase treatment and care for cancer patients. Dr. Gruber got his BA Degree from University of Pennsylvania in 1984 and after a while an MA Degree from Yale University in 1986. After he received his Doctorate Degree from Yale University in 1988, Dr. Gruber got accepted at the University of Pennsylvania Medical School and earned his Medical Degree in 1992 where he also finished his internship and residency. Later on, he did two fellowships one in medical oncology, at Johns Hopkins Hospital and one in clinical medical genetics at the University of Michigan. Dr. Gruber earned a series of honors and awards and is the author of over 150 publications. He has been in practice for more than 20 years and is affiliated with the USC Norris Comprehensive Cancer Center and Keck Medical Center of USC. During his career, he has also contributed to many research papers.

  • Education & Training


    Perelman at the University of Pennsylvania

    Medical School


    University of Pennsylvania Health System



    Johns Hopkins University


    Honors & Awards

    American Society of Clinical Investigation: Elected Member, 2003

    University of Michigan: League of Research Excellence, 2011

    USC: H. Leslie and Elaine S. Hoffman Cancer Research Chair, 2012

    Collaborative Group of the Americas on Inherited Colorectal Cancer : Lifetime Achievement Award, 2013

    Association of American Cancer Institute: Board of Directors, 2015

  • Board Certifications

    American Board of Internal Medicine - Oncology

  • Hospital & Practice

    Keck Hospital of USC - Medical Center

    Languages: English/Spanish

    (323) 442-8500

    1500 San Pablo St

    Los Angeles, California 90033

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    USC Norris Comprehensive Cancer Center

    Languages: English/Spanish

    (323) 865-3000

    1441 Eastlake Avenue

    Los Angeles, California 90033

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  • Publications & Memberships

    Dr. Stephen B. Gruber has contributed to 4 publications.

    Tumor-Infiltrating Lymphocytes, Crohn's-Like Lymphoid Reaction, and Survival From Colorectal Cancer.

    Rozek, L. S.,Schmit, S. L.,Greenson, J. K.,Tomsho, L. P.,Rennert, H. S.,Rennert, G.,Gruber, S. B.; J. Natl. Cancer Inst.. 2016 May 14.

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    Association of Interferon Regulatory Factor-4 Polymorphism rs12203592 With Divergent Melanoma Pathways.

    Gibbs, D. C.,Orlow, I.,Bramson, J. I.,Kanetsky, P. A.,Luo, L.,Kricker, A.,Armstrong, B. K.,Anton-Culver, H.,Gruber, S. B.,Marrett, L. D.,Gallagher, R. P.,Zanetti, R.,R...; J. Natl. Cancer Inst.. 2016 Feb 10.

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    Cross-cancer genome-wide analysis of lung, ovary, breast, prostate and colorectal cancer reveals novel pleiotropic associations.

    Fehringer, G.,Kraft, P.,Pharoah, P. D.,Eeles, R. A.,Chatterjee, N.,Schumacher, F. R.,Schildkraut, J. M.,Lindstrom, S.,Brennan, P.,Bickeböller, H.,Houlston, R. S.,Landi...; Cancer Res.. 2016 May 20.

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    The OncoArray Consortium: a Network for Understanding the Genetic Architecture of Common Cancers.

    Cancer Epidemiol Biomarkers Prev. 2016 Oct 3.

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    American Society of Clinical Oncology