Searching For Reliable Biomarkers for the Early Diagnosis of Mesothelioma

January 31st, 2012

According to recent findings of a 2012 German study, a microRNA identified as miR-103 could be a reliable biomarker for mesothelioma. This microRNA is a part of a group of microRNAs associated with cell division, stress response and the formation of new blood vessels, and showed promising sensitivity and specificity to malignant mesothelioma. The study suggests that deregulations of microRNAs may contribute to the development of human diseases. Published in the scientific journal PLoS One, the study stresses that to confirm these findings, miR-103 should be further investigated.

What is mesothelioma? Associated with asbestos exposure, this is a cancer of the lining of the lung and abdomen, incurable with present mesothelioma drugs. Because its symptoms may take as much as 20-50 to show, people affected may be clueless about their state. Symptoms in early stages are usually non-specific and when finally diagnosed, most patients are already in the final stages. Approximately 2,500-3,000 people are diagnosed with mesothelioma in the U.S. yearly, and it is estimated that by 2054, this number will rise to 71,000. This state of facts calls for the worldwide ardent search of mesothelioma centers, for new ways of early detection and mesothelioma treatment.

In their effort to identify reliable biomarkers sensitive enough to detect tumors at early stages and specific enough to avoid false positives, the German mesothelioma doctors also tried to use the least invasive method of observation. Their study included blood samples collected from 23 patients with aged 34-84, all diagnosed with malignant plural mesothelioma, and of who all had yet to undergo chemotherapy or radiation as part of treatment. Reportedly, in 75 percent to 80 percent of cases the presence of miR-103 was useful as a biomarker in distinguishing mesothelioma patients from cancer-free subjects.


Experimental Mesothelioma Drug Enters Phase 2 Trial

April 4th, 2011

In a major move against the deadly malignant mesothelioma an enzyme-based therapy for its treatment has entered its second phase. Read more »


Australian Woman Surviving Mesothelioma

March 16th, 2011

In a report in the Journal of Medical cases an article was published which quoted the survival of Australian woman in a mesothelioma case Read more »


Faulty DNA Repair Genes May Raise Mesothelioma Risk

February 11th, 2011

Asbestos is a fibrous material which has got excellent properties of heat retardation, electrical insulation and hardness with flexibility at the same time. Inhalation of these fibers Read more »


Gastric cancer drugs: A new hope for pleural mesothelioma patients

January 18th, 2011

Mesothelioma is a type of lung cancer which is caused due to inhalation of air borne asbestos fibers. Pleural mesothelioma is the most common type of mesothelioma. Read more »


Proton Therapy- An Effective Treatment for Mesothelioma now at Virginia University

December 2nd, 2010

The most independent and the largest amongst the only 8 mesothelioma cancer centers of the world offering the proton beam radiotherapy Read more »


A Protein Killer Could Treat All Cancers and Possibly All Illnesses

October 6th, 2010

A recent research study highly revealed that an experimental drug proved to be much more helpful for the Mesothelioma treatment where chemotherapy failed to perfectly respond. Read more »


A Mesothelioma Cancer Patient Survives – There is Hope

August 23rd, 2010

It happened at Brigham and Women’s Hospital in Boston, Massachusetts. Karen Grant was diagnosed with pleural mesothelioma tumor Read more »


Cold Plasma Coagulation as a mesothelioma treatment

July 6th, 2010

It is widely known that mesothelioma is a difficult type of cancer to treat and we also know that each year another type of treatment is presented. Read more »


UK team may discover Mesothelioma vaccine

July 2nd, 2010

Mesothelioma cancer centers and mesothelioma doctors all over the world are constantly searching for new ways to treat the disease, but with little luck. Even so, a team at the Cardiff Research center Read more »


Contact a Mesothelioma Doctor Now!

Free mesothelioma case evaluation! Find out more information about your legal rights.

Name:

Email:

Phone:

State / Location:

Comments:

Archived Mesothelioma News
  • Mesothelioma News Categories
  • Other Resources